2005). In conclusion, Pyr-1 is a book pyridazinone derivative which has effective anti-cancer activity at nanomolar and low micromolar concentrations on 22 individual cancer tumor cell lines. cytometry. Both protein and RNA appearance amounts had been examined by quantitative real-time PCR and Traditional western blotting assays, respectively. Pyr-1 induced apoptosis in severe promyelocytic leukemia cells … Continue reading 2005)